In short: What to do in Panama? Visit the canal and the Casco Viejo in Panama City, escape to the San Blas islands, dive at Bocas del Toro, taste coffee in the Boquete highlands, explore Coiba, “the Galápagos of Panama”, and travel back in time at the forts of Portobelo. A concentrate of Central America, between two oceans.
Small in size, immense in variety: that's Panama. In a single trip, you go from the skyscrapers of a bustling capital to near-deserted islands, from tropical forests to highland coffee plantations. Here are the must-sees of Panama, the ones I truly recommend to my travelers, with a few field tips to make the most of them.

1. The Panama Canal
Impossible to come without seeing this marvel of human engineering. At the locks of Miraflores, you watch from a terrace as giant ships rise, meter by meter. The visitor center (museum + film) costs around US$17-22. To understand its full history and its 2016 expansion, read our complete guide to the Panama Canal.
2. The Casco Viejo, historic heart of Panama City
UNESCO-listed, the Old Town is the capital's most charming quarter: cobbled lanes, colorful facades, baroque churches, shaded squares, and rooftops from which to admire the modern skyline at sunset. You wander it on foot, from café to craft shop. It's also the best place to taste Panamanian cuisine and hear jazz in the evening.
3. The Biomuseo
On the Calzada de Amador, this explosion of colors signed by Frank Gehry tells a fascinating story: how the birth of the Panama isthmus, 3 million years ago, upended the planet's ocean currents and biodiversity. A playful, spectacular museum, ideal for families.
4. The San Blas islands (Guna Yala)
Paradise, the authentic version. The archipelago of Guna Yala counts nearly 365 islands, governed by the Guna people who keep their way of life alive there. Coconut palms, turquoise water, stilt huts: you come to disconnect, sleep on a tiny island, and buy molas, those hand-sewn textiles. Bring cash and expect deliberately rustic comfort.

5. Bocas del Toro
On the Caribbean side, the archipelago of Bocas del Toro lines up nine main islands and a unique Afro-Caribbean vibe. Snorkeling over the reefs, dream beaches (Red Frog Beach, Cayo Zapatilla), dolphin outings, mangroves, and a laid-back nightlife. Perfect for slowing down for several days.
6. Boquete, coffee and Volcán Barú
In the cool heights of Chiriquí (1,200 m), Boquete is the kingdom of coffee — including the famous Geisha, awarded worldwide. Visit a finca, taste at the source, go birdwatching (the quetzal!) or, if you're fit, climb Volcán Barú, the country's highest point, from which you can glimpse both oceans on a clear day.
7. Coiba, “the Galápagos of Panama”
A former prison island turned national park and UNESCO-listed marine reserve, Coiba shelters one of the region's richest marine ecosystems: sharks, rays, turtles, schools of fish. A dream for divers and snorkelers, departing from Santa Catalina.
8. The forts of Portobelo
On the Caribbean coast, Portobelo was once the port through which the gold of the Americas passed. Its Spanish forts, UNESCO-listed, and its Cristo Negro church plunge the traveler into the history of galleons and pirates. A perfect stop between culture and nature.

9. Watching humpback whales
From July to October, the Pacific Panamanian becomes one of the best places in the world to see humpback whales. The Gulf of Chiriquí, Coiba, or the Pearl Islands: the boat outings offer an unforgettable show. It's all in our article whale watching in Panama.
10. Rainforest at the capital's gates
It's often overlooked: less than an hour from Panama City, the national park of Soberanía and the region of Gamboa plunge the traveler into deep jungle, along the canal. Trails renowned for birdwatching (Pipeline Road is legendary among birders), sloths, monkeys, and caimans: half a day is enough to radically change the mood without leaving the city's surroundings.
11. Meeting the Emberá people
Along the Río Chagres, several Emberá communities welcome visitors to share their culture: dugout canoe, dances, crafts, plant knowledge. An encounter to experience with respect, favoring initiatives led by the communities themselves, in the spirit of responsible tourism.
Field advice
- Book the logistical must-dos in advance (San Blas, Coiba, whale outings): places are limited.
- Keep cash : essential in San Blas and rural areas.
- Alternate the rhythms : one city day, one nature day, one lazy day — that's the key to a balanced stay.
- Respect the Indigenous peoples and the wildlife: always ask before photographing, don't feed the animals.
How to combine it all?
Two weeks let you link most of these sites without rushing: follow our 15-day Panama itinerary. To choose the best time, see when to visit Panama, and to price it all, our Panama travel budget. Want to get off the beaten path? Our Secret Panama in 7 experiences will inspire you.
Frequently Asked Questions
What are Panama's must-sees?
The Panama Canal, the Casco Viejo, the San Blas islands, Bocas del Toro, Boquete and its coffee, Coiba, and the forts of Portobelo form the heart of a first trip.
How long do you need to visit Panama?
A week for the essentials (capital, canal, one escape), ideally two weeks to link the two oceans, the mountains, and the islands.
Can you visit the Panama Canal?
Yes, easily: the Miraflores visitor center lets you watch ships pass from a terrace, with a museum and explanatory film.
Is Panama good for diving?
Yes, notably at Coiba (Pacific) and Bocas del Toro (Caribbean), two spots renowned for the richness of their marine life.
Shall we select your Panamanian experiences?
At Toucan Discovery, an inbound agency in Central America, we compose your trip around the experiences that suit you. Request your quote: reply within 24 hours. Where create your trip directly on Toucan Dynamics, and Contact us.
Plan your trip to Central America.
A Toucan Discovery advisor helps you transform these ideas into a tailor-made itinerary — Costa Rica, Panama, Nicaragua. Real-time availability, instant quote.
Plan my trip